ISOTRETINOIN - Oral

Clinical Indication

Severe acne

Comments

Isotretinoin – changes to prescribing guidance and additional risk minimisation measures – GOV.UK

MHRA Advice: Oral retinoid medicines: revised and simplified pregnancy prevention educational materials for healthcare professionals and women

Recommendations | Acne vulgaris: management | Guidance | NICE

Date of classification

May 2026

Red

Medicines which should be prescribed only in a specialist setting usually within a secondary or tertiary care service. NB: Some highly specialised RED medicines e.g. injectable treatments for cancer are not included on the LLR APC website list.