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Last updated: 05/09/2022

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Drug Name Classification Clinical Indication Comments
Alimemazine (NEW) Red

LPT only. Insomnia for new patients (under 18 yr olds) if melatonin and/or another sedating antihistamine has failed or is inappropriate.  May be continued into adulthood if patient requires it after transition.

ALIMEMAZINE (UPDATED) Do not prescribe Various

All other new patients not covered in alternative traffic lights Current patients should be discussed with the prescribing specialist and not have treatment stopped abruptly without appropriate review.

AVATROMBOPAG (Doptelet®) (UPDATED) Red For treating primary chronic immune thrombocytopenia

NICE TA853

DIENOGEST (UPDATED) Red Treatment of endometriosis.
ETHAMBUTOL Red Tuberculosis treatment

Red for treatment of TB

Hyaluronidase/Trehalose Eye Drops(Thealoz Duo®) (NEW) Yellow Ocular Lubricant

For patients with dexterity issues unable to use 1st line recommendation in ocular lubricant guideline

Hydrocortisone Eye Drops(Softacort®) (NEW) Yellow Mild non-infectious allergic or inflammatory conjunctival diseases

When preservative free preparation required

Isoniazid Red Tuberculosis treatment

Red for treatment of TB

NALOXONE nasal spray (Nyxoid®) (UPDATED) Red Opioid overdose

Turning point or on TTO from secondary care only

PENTHROX®(Methoxyflurane) (UPDATED) Red Analgesia

For use in Emergency department or for  removal of brachytherapy only

PYRAZINAMIDE Red Tuberculosis treatment

Red for treatment of TB

Rifampicin Red Tuberculosis treatment

Red for treatment of TB

RIFAMPICIN /ISONIAZID AND PYRAZINAMIDE Red Tuberculosis treatment

Red for treatment of TB

RIFAMPICIN/ISONIAZID/PYRAZINAMIDE/ETHAMBUTOL (Voractiv) (UPDATED) Red Tuberculosis Treatment

Treatment of TB

RIFAXIMIN(Targaxan®) (UPDATED) Red Small intestinal overgrowth

Small intestinal overgrowth

Tiopronin (NEW) Red Cystinuria
Upadacitinib (Rinvoq®) (NEW) Red For treating moderately to severely active ulcerative colitis

NICE TA856

Other Updates on this Website

Recent documents from LLR APC and TAS


About the Leicester, Leicestershire and Rutland Area Prescribing Committee

In common with other local health communities, the Leicester, Leicestershire and Rutland Area Prescribing Committee (LLR APC) acknowledges the benefits of having a Leicestershire Health Community-wide strategy for the prescribing of specialist medicines and the managed entry of new drugs and related technologies.

Leicestershire Health Community comprises the Leicester, Leicestershire and Rutland Integrated Care Board, University Hospitals of Leicester (UHL) NHS Trust and Leicestershire Partnership NHS Trust (LPT), amongst which there is a total consensus on the need for this strategy, and the LLR APC has been in place since 2005. Learn more