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Last updated: 05/09/2022

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Drug Name Classification Clinical Indication Comments
ALISKIREN Orange Existing patients with Hypertension

Full SCA

AMANTADINE Yellow Prolonged disorder of consciousness
AMISULPRIDE (UPDATED) Yellow Schizophrenia

Antipsychotic prescribing guide

ANGIOTENSIN II (Giapreza® ) (NEW) Grey Hypotension in adults with septic or other distributive shock
ANTIPSYCHOTICS-Atypical (UPDATED) Yellow

See Antipsychotic prescribing guide

ARIPIPRAZOLE LONG-ACTING INJECTION (Abilify Maintena®) (UPDATED) Yellow Maintenance treatment of schizophrenia in patients currently stabilised on oral aripiprazole

See Antipsychotic Prescribing Guide

ARIPIPRAZOLE oral (UPDATED) Yellow Schizophrenia. Treatment and recurrence of mania. Control of agitation and disturbed behaviour in schizophrenia

See Antipsychotic Prescribing Guide

BALSALAZIDE (UPDATED) Yellow Ulcerative colitis
BULEVIRTIDE (Hepcludex ®) (NEW) Grey Chronic hepatitis delta virus (HDV) infection in plasma (or serum) HDV-RNA positive adult patients with compensated liver disease.
CATRIDECACOG (Novothirteen ®) (NEW) Grey Long term prophylaxis of bleeding in patients with congenital factor XIII A-subunit deficiency and bleeding episodes during regular prophylaxis.
CYANOCOBALAMIN (UPDATED) Do not prescribe Dietary supplementation of Vitamin B12
CYANOCOBALMIN (Orobalin ®1mg tablet) (NEW) Green Higher strength cyanocobalmin oral product

Only to be used where there is malabsorption of Vitamin B12 in needle phobic patients, patients with mobility issues unable/ unsuitable to attend for injections or patients where injection is not tolerated preventing the use of hydroxycobalamin injections.

DANTROLENE Capsules (NEW) Orange Chronic Spasticity in Adults

Full SCA

DAPAGLIFLOZIN (Forxiga®) Green CKD in adults

In line with NICE TA775

See CKD pathway for more information

 

DAPSONE Red Dermatology
DELAFLOXACIN MEGLUMINE (Quofenix®) Red Acute bacterial skin and skin structure infections
DEXAMETHASONE / LEVOFLOXACIN EYE DROPS (Ducressa®) Grey Prevention and treatment of inflammation and prevention of infection associated with cataract surgery in adults.
DIROXIMEL FUMERATE (Vumerity®) Red Relapsing-remitting multiple sclerosis

In line with NICE TA794

DOXAZOSIN M/R TABLETS Do not prescribe Hypertension
FAMOTIDINE Green H2 antagonist
FARICIMAB (Vabysmo®) (NEW) Red Wet age-related macular degeneration

In line with NICE TA800

FILGOTINIB (Jyseleca®) Red Moderate to severe active ulcerative colitis

In line with NICE TA792

Implementation date 1st September 2022

FINERENONE (Kerendia®) Grey Treatment of chronic kidney disease (stage 3 and 4 with albuminuria) associated with type 2 diabetes in adults.
FLUPENTIXOL DECANOATE (UPDATED) Yellow Schizophrenia

See Antipsychotic Prescribing Guide

FLUPHENAZINE DECANOATE (UPDATED) Yellow Schizophrenia

See Antipsychotic Prescribing Guide

FORMOTEROL/BUDESONIDE/GLYCOPYRRONIUM INHALER (Trixeo Aerospace®) Do not prescribe Moderate to severe COPD

Reviewed by the Respiratory Prescribing Group May 2022

HALOPERIDOL DECANOATE (UPDATED) Yellow Schizophrenia

See Antipsychotic Prescribing Guide

HYDROXYCHLOROQUINE Yellow Dermatological conditions

Eye checks to be organised by secondary care

INCLISIRAN (Leqvio®) Green Treating primary hypercholesterolaemia or mixed dyslipidaemia. SECONDARY PREVENTION ONLY as per NICE TA733

For prescribers who feel competent to use this medication.

In line with NICE TA733.

For further related guidance please see the Cardiovascular Guidelines page. This page also includes an interim inclisiran pathway.

 

IQoro® Grey Neuromuscular training device
LURASIDONE (UPDATED) Yellow schizophrenia

See Antipsychotic Prescribing Guide

LYUMJEV Green Fast acting insulin for adults with diabetes mellitus
MEPACRINE Red Refractory giardiasis
MESALAZINE ORAL (prescribe by brand) (UPDATED) Yellow Ulcerative colitis, Crohn's disease and paediatric colitis

Monitoring for paediatrics done by secondary care

OLANZAPINE Oral (UPDATED) Yellow Schizophrenia. Combination therapy for mania. Preventing recurrence in bipolar disorder. Monotherapy for mania. Control of agitation and disturbed behaviour in schizophrenia or mania. Personality disorder.

See Antipsychotic Prescribing Guide

ORITAVANCIN (Tenkasi®) Grey Acute bacterial skin and skin structure infections
PALIPERIDONE PALMITATE Long-Acting Injection (UPDATED) Yellow Maintenance in schizophrenia in patients previously responsive to risperidone.

See Antipsychotic Prescribing Guide

PERINDOPRIL ARGINE Do not prescribe Hypertension
PLENVU Red Bowel cleansing
POTASSIUM PERMANGANATE Red Dermatology

External use only

QUETIAPINE (UPDATED) Yellow Schizophrenia. Mania (either alone or in combination with mood stabilisers). Depression in bipolar disorder. Adjunctive treatment in major depressive disorder. Personality disorder.

See Antipsychotic Prescribing Guide

RISPERIDONE LONG-ACTING INJECTION (Risperdal Consta®) (UPDATED) Yellow Schizophrenia and other psychoses in patients tolerant to oral risperidone.

See Antipsychotic Prescribing Guide

RISPERIDONE Oral (UPDATED) Yellow Acute and chronic psychoses. Mania. Short term (up to 6 weeks) of persistent aggression in patients with moderate to severe AD. Short term (up to 6 weeks) treatment of persistent aggression in conduct disorder. Personality disorder.

See Antipsychotic Prescribing Guide

ROMOSOZUMAB (Evenity®) Red Severe osteoporosis

In line with NICE TA791

Implementation date 25th August 2022

SOMATROGON (Ngenla®) Grey Treatment of children and adolescents from 3 years of age with growth disturbance due to insufficient secretion of growth hormone.
STRONTIUM RANELATE Red Severe postmenopausal osteoporosis to reduce the risk of vertebral & non-vertebral fractures in patients without established cardiovascular disease when other treatments are contraindicated
SUCRALFATE ENEMAS Red Radiation proctitis
SULFASALAZINE ORAL & RECTAL Orange Ulcerative colitis and Crohn's disease

Shared care request is mandatory
Full SCA

TransiSoft® Do not prescribe Chronic constipation, use usually limited to 2 weeks

Not to be confused with other macrogol products such as Macrogol oral powder compound e.g. Laxido or Movicol

TRIFAROTENE (Aklief®) (NEW) Grey Cutaneous treatment of Acne Vulgaris
VOXELTOR Red Haemolytic anaemia in adults and paediatric patients 12 years of age and older with sickle cell disease

Under the EAMS scheme

ZUCLOPENTHIXOL DECANOATE (Clopixol® Depot and Clopixol® Conc.) (UPDATED) Yellow Schizophrenia

See Antipsychotic Prescribing Guide

Other Updates on this Website

Recent documents from LLR APC and TAS


About the Leicester, Leicestershire and Rutland Area Prescribing Committee

In common with other local health communities, the Leicester, Leicestershire and Rutland Area Prescribing Committee (LLR APC) acknowledges the benefits of having a Leicestershire Health Community-wide strategy for the prescribing of specialist medicines and the managed entry of new drugs and related technologies.

Leicestershire Health Community comprises the Leicester, Leicestershire and Rutland Integrated Care Board, University Hospitals of Leicester (UHL) NHS Trust and Leicestershire Partnership NHS Trust (LPT), amongst which there is a total consensus on the need for this strategy, and the LLR APC has been in place since 2005. Learn more