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Last updated: 05/09/2022

Other updates on this site
Drug Name Classification Clinical Indication Comments
1mg Estradiol and 100mg Micronised progesterone(Bijuve) Green Continuous combined hormone replacement therapy (HRT) for estrogen deficiency symptoms in postmenopausal women
ABROCITINIB (Cibinqo ®) Red Treatment of moderate-to-severe atopic dermatitis in adults and adolescents 12 years and older who are candidates for systemic therapy
ACETYLCYSTEINE EFFERVESCENT TABLETS Green COPD Reduction of sputum viscosity

LMSG Mucolytic prescribing guide

Effervescent tablets only, prescribe generically. Capsules not to be prescribed.

Advagraf Prolonged Release (Tacrolimus) Red immunosuppression
Atogepant (NEW) Yellow preventing migraine

TA973

For preventing migraines

Beclometasone extra-fine/ Formoterol Inhaler (LUFORBEC pMDI) (NEW) Green Asthma and COPD

Asthma: 100/6 mcg/dose and 200/6 mcg/dose

COPD: 100/6 mcg/dose only

Cefepime dihydrochloride monohydrate/Enmetazobactam) powder for concentrate for solution for infusion (2 g/0.5 g) Exblifep Grey Complicated UTIs including pyelonephritis, hospital-acquired pneumonia, and treatment of bacteraemia in association (or potentially linked) with these infections
Cytisine 1.5mg Tablets (NEW) Red For smoking cessation

*25 day course only

In case of treatment failure, the treatment should be discontinued and may be resumed after 2 to 3 months

DENOSUMAB 120mg (Xgeva®) (UPDATED) Red Prevention of skeletal related events for myeloma patients with CKD (GFR <10ml/min)
DexcomONE plus Yellow Diabetes glucose monitoring for those included on the LLRAPC position statement
FLUOCINOLONE ACETONIDE (Synalar®) Green Inflammatory skin disorders

Synalar 0.00625% or 0.025% strength

Available as gel, cream and ointment.

Freestyle Libre 2+ Yellow

Diabetes glucose monitoring for those included on the LLRAPC position statement. (updated software and sensor; plan to discontinue Freestyle Libre 2 over the next 12 months – July 2023 to July 2024)

ICOSAPENT ETHYL (Vazkepa ®) (UPDATED) Green Raised triglycerides in patients with CVD

LLR Lipid pathway

IVERMECTIN TABLETS (NEW) Yellow Gastrointestinal strongyloidiasis (anguillulosis) and suspected or diagnosed microfilaraemia
IVERMECTIN TABLETS (NEW) Green Human sarcoptic scabies
Patiromer (Veltassa) Red Hyperkalaemia
Quinidine Red KCNT1 gene mutation related Early Infantile epileptic encephalopathy
QUOFENIX Red Antibiotic
Rekambys (Rilpivirine) Red Stable HIV infection
Remdesivir and Tixagevimab Plus Cilgavimab Red for treating COVID-19

TA971

Rifapentine Red Treatment of latent tuberculosis, especially in patients with social exclusion and at high risk of noncompletion, or those with preexisting liver disease
Rifaximin Red small intestinal bacterial overgrowth
Rilecitinib (NEW) Red

50 mg once daily, consider discontinuation of treatment if no response after 36 weeks. A patient card should be provided. NICE TA 958

The manufacturer of Litfulo® has provided a Prescriber Guide, which includes a prescriber checklist.

SIALANAR Yellow Drooling in chronic neurological disorders
TACROLIMUS Ointment Green Dermatitis

Protopic 0.03% and 0.1% ointment

VEDOLIZUMAB (Entyvio®) Red Moderate to severe active UC or Crohn’s disease

Devices: pen, pre-filled syringe or solution for infusion

Verkazia (Ciclosporin) eye drops Yellow Treatment of severe vernal keratoconjunctivitis (VKC) in children from 4 years of age and adolescence
Visuxl Green Visuxl is indicated for the treatment of dry eye and corneal healingpost surgery

Sodium hyaluronate
0.1%, co-enzyme Q10
0.1%, vitamin E 0.5%

VOCABRIA Red Stable HIV infection

Cabotegravir (Vocabria)

Voxelotor Red Reducing need for transfusion in sickle cell disease

TA981

Oxbryta 500 mg film-coated tablets

Xonvea Do not prescribe nausea , vomiting in pregancy

(Doxylamine & pyridoxine)

Zalkya Green Medical treatment of endometriosis

Dienogest (Zalkya)

Other Updates on this Website

Recent documents from LLR APC and TAS


About the Leicester, Leicestershire and Rutland Area Prescribing Committee

In common with other local health communities, the Leicester, Leicestershire and Rutland Area Prescribing Committee (LLR APC) acknowledges the benefits of having a Leicestershire Health Community-wide strategy for the prescribing of specialist medicines and the managed entry of new drugs and related technologies.

Leicestershire Health Community comprises the Leicester, Leicestershire and Rutland Integrated Care Board, University Hospitals of Leicester (UHL) NHS Trust and Leicestershire Partnership NHS Trust (LPT), amongst which there is a total consensus on the need for this strategy, and the LLR APC has been in place since 2005. Learn more